山葵萃取文獻
抗菌
1.Wasalexins A and B, new phytoalexins from wasabi: Isolation, synthesis, and antifungal activity
2.Overexpression of the wasabi defensin gene confers enhanced resistance to blast fungus (Magnaporthe grisea) in transgenic rice
https://link.springer.com/article/10.1007/s00122-001-0817-9
3.Bactericidal activity of wasabi (Wasabia japonica) against Helicobacter pylori
4.Stable integration and expression of wasabi defensin gene in “Egusi” melon (Colocynthis citrullus L.) confers resistance to Fusarium wilt and Alternaria leaf spot
https://link.springer.com/article/10.1007/s00299-010-0880-2
5.Retransformation of Marker-Free Potato for Enhanced Resistance Against Fungal Pathogens by Pyramiding Chitinase and Wasabi Defensin Genes
https://link.springer.com/article/10.1007/s12033-014-9760-2
6.Antibacterial Activities of Wasabi against Escherichia coli O157:H7 and Staphylococcus aureus
https://www.frontiersin.org/articles/10.3389/fmicb.2016.01403/full
7.Improvement Effects of Wasabi (Wasabia japonica) Leaves and Allyl Isothiocyanate on Stomach Lesions of Mongolian Gerbils Infected with Helicobacter pylori
https://journals.sagepub.com/doi/abs/10.1177/1934578X1701200431
8.The rodent model of impaired gastric motility induced by allyl isothiocyanate, a pungent ingredient of wasabi, to evaluate therapeutic agents for functional dyspepsia
https://www.sciencedirect.com/science/article/pii/S1347861320301043
9.The influence of wasabi on the gut microbiota of high-carbohydrate, high-fat diet-induced hypertensive Wistar rats
https://www.nature.com/articles/s41371-020-0359-8
抗氧化
1.Molecular Mechanisms Underlying Anti-Inflammatory Actions of 6-(Methylsulfinyl)hexyl Isothiocyanate Derived from Wasabi (Wasabia japonica)
https://www.hindawi.com/journals/aps/2012/614046/
2.Involvement of AMP-activated Protein Kinase α/Nuclear Factor (Erythroid-derived 2) Like 2-iniatived Signaling Pathway in Cytoprotective Effects of Wasabi 6-(Methylsulfinyl) Hexyl Isothiocyanate
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8984653/
3.DNA Microarray Highlights Nrf2-Mediated Neuron Protection Targeted by Wasabi-Derived Isothiocyanates in IMR-32 Cells
https://journals.sagepub.com/doi/full/10.4137/GRSB.S39440
4.Comparative Gene Expression Profiling in Cultured Cell Lines after Treatment with Wasabi-derived Isothiocyanates
https://kimika.pfcs.org.ph/index.php/kimika/article/view/249
5.Takotsubo cardiomyopathy triggered by wasabi consumption: can sushi break your heart?
https://casereports.bmj.com/content/12/9/e230065.abstract
6.Flavonoid and Phenolic Acids Content and In Vitro Study of the Potential Anti-Aging Properties of Eutrema japonicum (Miq.) Koidz Cultivated in Wasabi Farm Poland
https://www.mdpi.com/1422-0067/22/12/6219
控制血糖
1.Glycogen Synthase Kinase-3β Inhibition of 6-(Methylsulfinyl)hexyl Isothiocyanate Derived from Wasabi (Wasabia japonica Matsum)
https://academic.oup.com/bbb/article/75/1/136/5950052?login=false
抑制癌細胞
1.Suppressive effect of wasabi (pungent Japanese spice) on gastric carcinogenesis induced by MNNG in rats
https://www.tandfonline.com/doi/abs/10.1080/01635589109514140
2.Anti-carcinogenic activity of 6-methylsulfinylhexyl isothiocyanate-, an active anti-proliferative principal of wasabi (Eutrema wasabi Maxim.)
https://link.springer.com/article/10.1023/A:1007918508115
3.Transcriptional regulation of nicotinamide adenine dinucleotide phosphate: quinone oxidoreductase in murine hepatoma cells by 6-(methylsufinyl)hexyl isothiocyanate, an active principle of wasabi (Eutrema wasabi Maxim)
4.Antiplatelet and anticancer isothiocyanates in Japanese domestic horseradish, Wasabi
5.Identification of 6-methylsulfinylhexyl isothiocyanate as an apoptosis-inducing component in wasabi
6.Selective sensitivity to wasabi-derived 6-(methylsulfinyl)hexyl isothiocyanate of human breast cancer and melanoma cell lines studied in vitro
7.Colon Cancer Proliferating Desulfosinigrin in Wasabi (Wasabia japonica)
https://www.tandfonline.com/doi/abs/10.1207/s15327914nc4802_11
8.Chemoprevention of 1,2-dimethylhydrazine-induced colonic preneoplastic lesions in Fischer rats by 6-methylsulfinylhexyl isothiocyanate, a wasabi derivative
https://www.spandidos-publications.com/10.3892/ol_00000048?text=fulltext
9.Effect of Wasabi Component 6-(Methylsulfinyl)hexyl Isothiocyanate and Derivatives on Human Pancreatic Cancer Cells
https://www.hindawi.com/journals/ecam/2014/494739/
10.Wasabi-Derived 6-(Methylsulfinyl)Hexyl Isothiocyanate Induces Apoptosis in Human Breast Cancer by Possible Involvement of the NF-κB Pathways
11.Differential Pharmacological Activities of Oxygen Numbers on the Sulfoxide Moiety of Wasabi Compound 6-(Methylsulfinyl) Hexyl Isothiocyanate in Human Oral Cancer Cells
https://www.mdpi.com/1420-3049/23/10/2427
12.Involvement of ERK1/2-mediated ELK1/CHOP/DR5 pathway in 6-(methylsulfinyl)hexyl isothiocyanate-induced apoptosis of colorectal cancer cells
https://www.tandfonline.com/doi/full/10.1080/09168451.2019.1574206
13.Wasabi Compound 6-(Methylsulfinyl) Hexyl Isothiocyanate Induces Cell Death with Coexisting Mitotic Arrest and Autophagy in Human Chronic Myelogenous Leukemia K562 Cells
https://www.mdpi.com/2218-273X/9/12/774
促進膠原蛋白生產
1.The effect of isosaponarin isolated from wasabi leaf on collagen synthesis in human fibroblasts and its underlying mechanism
https://link.springer.com/article/10.1007/s11418-010-0412-y
增強免疫力
1.Drugs that act on the immune system: immunosuppressive and immunostimulatory drugs
https://www.sciencedirect.com/science/article/abs/pii/B9780444626356000383
抗發炎
1.Molecular Mechanisms Underlying Anti-Inflammatory Actions of 6-(Methylsulfinyl)hexyl Isothiocyanate Derived from Wasabi (Wasabia japonica)
https://www.hindawi.com/journals/aps/2012/614046/
2.Anti-obesity Effects of Wasabi Leaf Extract on Rats Fed a High-fat Diet are Related to Upregulation of mRNA Expression of β3-adrenergic Receptors in Interscapular Brown Adipose Tissue
https://www.jstage.jst.go.jp/article/fstr/22/5/22_665/_article/-char/ja/
控制體重
1.Anti-obesity effects of hot water extract from Wasabi (Wasabia japonica Matsum.) leaves in mice fed high-fat diets
https://synapse.koreamed.org/articles/1051299
2.Wasabi leaf extracts attenuate adipocyte hypertrophy through PPARγ and AMPK
https://academic.oup.com/bbb/article/80/8/1594/5938185?login=false
3.Isolation and Identification of Components from Wasabi (Wasabia japonica Matsumura) Flowers and Investigation of Their Antioxidant and Anti-inflammatory Activities
https://www.jstage.jst.go.jp/article/fstr/25/3/25_449/_html/-char/en
止痛
1.Response of Drosophila to Wasabi Is Mediated by painless, the Fly Homolog of Mammalian TRPA1/ANKTM1
https://pubmed.ncbi.nlm.nih.gov/16647259/
2.The Effect of Wasabi Rhizome Extract on Atopic Dermatitis-Like Symptoms in HR-1 Hairless Mice
https://www.jstage.jst.go.jp/article/jnsv/55/2/55_2_195/_article/-char/ja/
3.Wasabi and a Volatile Anesthetic
https://pubs.asahq.org/anesthesiology/article/112/6/1309/10210/Wasabi-and-a-Volatile-Anesthetic
